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American Cruise Line Cruise Deals
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
Featured American Cruise Line Deals
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NAPA VALLEY CRUISE
Weekly Special: Save up to $1200 per stateroom
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Columbia & Snake River Cruises
Free Airfare & Savings: Save up to $1,000 + Free Airfare on select sailings
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Mississippi River Cruises
Free Airfare & Savings: Save up to $1,200 + Free Airfare on select sailings
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Mississippi River r/t New Orleans
Free Airfare + Save up to $1200 per stateroom: Paddlewheeler Cruise
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PUGET SOUND & SAN JUAN ISLANDS
Save up to $1500 per stateroom on select sailings
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Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
- Complimentary Wi-Fi
- Complimentary cocktail hour held each evening
- Afternoon tea service in the Sky Lounge
- Breakfast room service
- Culinary program featuring locally sourced ingredients
Best American Cruise Line Deals by Destination
COLUMBIA & SNAKE RIVER CRUISE
7 Day US & Canada River Cruises
American Serenade New Ship!
New Orleans to Memphis
Apr 20 - Dec 7, 2023
American Serenade New Ship!
New Orleans to Memphis
Apr 20 - Dec 7, 2023
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
COLUMBIA & SNAKE RIVER CRUISE
7 Day US & Canada River Cruises
American Symphony New Ship!
New Orleans to Memphis
Apr 14 - Nov 17, 2023
American Symphony New Ship!
New Orleans to Memphis
Apr 14 - Nov 17, 2023
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,495
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,710
COLUMBIA & SNAKE RIVER CRUISE
- Free Airfare & Savings: Save up to $1,000 + Free Airfare on Columbia & Snake Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,710
Fall Foliage Cruise
7 Day US & Canada River Cruises
American Independence
Roundtrip New York City
Oct 1, 2023 - Oct 21, 2024
American Independence
Roundtrip New York City
Oct 1, 2023 - Oct 21, 2024
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,650
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,470
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,580
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,220
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,220
Memphis - Nashville
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,790
Round-Trip New Orleans
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Free Airfare + Save up to $1200 per stateroom: Paddlewheeler Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,895
Mississippi River Cruise
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,740
Mississippi River Cruise
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,740
Mississippi River Cruise
7 Day US & Canada River Cruises
American Serenade New Ship!
New Orleans to Memphis
Apr 20 - Dec 7, 2023
American Serenade New Ship!
New Orleans to Memphis
Apr 20 - Dec 7, 2023
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
Mississippi River Cruise
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
New Orleans - Memphis
7 Day US & Canada River Cruises
American Symphony New Ship!
New Orleans to Memphis
Apr 14 - Nov 17, 2023
American Symphony New Ship!
New Orleans to Memphis
Apr 14 - Nov 17, 2023
- Free Airfare & Savings: Save up to $1,200 + Free Airfare on Mississippi Cruises
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,745
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,915
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,140
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,505
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,505
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,605
New England Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,370
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,395
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,650
Great Florida Rivers
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,895
Southern Charm Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,460
Southern Charm Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,460
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,555
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,935
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,800
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,870
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,790
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,790
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,175
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Symphony New Ship!
Saint Louis to Saint Paul
Jul 7 - Oct 13, 2023
American Symphony New Ship!
Saint Louis to Saint Paul
Jul 7 - Oct 13, 2023
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
Upper Mississippi River Cruise
8 Day US & Canada River Cruises
American Serenade New Ship!
Saint Louis to Saint Paul
Sep 7 - Oct 5, 2023
American Serenade New Ship!
Saint Louis to Saint Paul
Sep 7 - Oct 5, 2023
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,065
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,365
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,315
San Francisco Bay
- Weekly Special: Save up to $1200 per stateroom
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,935
Puget Sound & San Juan Islands
- PUGET SOUND & SAN JUAN ISLANDS:: Save up to $1500 per stateroom
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,880
Grand Puget Sound
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,540
Grand Puget Sound
- PUGET SOUND & SAN JUAN ISLANDS:: Save up to $1500 per stateroom
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,180
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
