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American Cruise Line Deals

American Cruise Line Cruise Deals

American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.

Featured American Cruise Line Deals

  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More! View Details
    • Complimentary cocktail hour held each evening
    • Afternoon tea service in the Sky Lounge
    • Breakfast room service

Best American Cruise Line Deals by Destination

8 Day US & Canada River Cruises
American Pride
Portland/Oregon to Clarkston
Apr 27, 2025 - Nov 9, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,485
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada River Cruises
American Pride
Clarkston to Portland/Oregon
May 4, 2025 - Nov 2, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,787
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada Eastern
American West
Clarkston to Portland/Oregon
May 11 - Oct 12, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,876
8 Day US & Canada River Cruises
American West
Clarkston to Portland/Oregon
May 11, 2025 - Jul 20, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,876
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada River Cruises
American Song
Clarkston to Portland/Oregon
May 6, 2025 - Nov 4, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,559
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada River Cruises
American Harmony
Clarkston to Portland/Oregon
May 2, 2025 - Oct 17, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,054
7 Day Hudson River Cruise
American Glory
Albany to New York City
Oct 7 & 21, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,614
Fall Foliage Cruise
7 Day Hudson River Cruise
American Glory
New York City to Albany
Sep 30 & Oct 14, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,861
Fall Foliage Cruise
7 Day Hudson River Cruise
American Glory
New York City to Albany
Oct 5 & 19, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,356
7 Day Hudson River Cruise
American Glory
Albany to New York City
Oct 12 & 26, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,356
Mississippi River Cruise
7 Day US & Canada River Cruises
American Heritage
Roundtrip New Orleans
Apr 28, 2025 - May 28, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,881
Mississippi River Cruise
8 Day US & Canada River Cruises
American Splendor
New Orleans to Memphis
May 6, 2025 - Jun 3, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,253
Mississippi River Cruise
8 Day US & Canada River Cruises
American Splendor
Memphis to New Orleans
Apr 29, 2025 - Nov 11, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,866
Mississippi River Cruise
8 Day US & Canada River Cruises
American Serenade
Memphis to New Orleans
Apr 26, 2025 - Oct 23, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
Mississippi River Cruise
8 Day US & Canada River Cruises
American Symphony
New Orleans to Memphis
Mar 4 - Dec 24, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,223
7 Day New England Cruise
American Glory
New York City to Boston
May 5, 2025 & May 22, 2027
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,693
7 Day New England Cruises
American Independence
New York City to Boston
May 26, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,782
7 Day New England Cruise
American Eagle
New York City to Boston
Jul 29, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,911
7 Day New England Cruise
American Glory
Roundtrip Boston
May 12, 2025 - Sep 21, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,643
7 Day New England Cruise
American Legend
Roundtrip Boston
Jun 13 - Sep 19, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,965
7 Day New England Cruise
American Glory
Boston to New York City
Sep 28, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,000
7 Day New England Cruise
American Pioneer
New York City to Boston
Apr 16 & 30, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,703
10 Day New England Cruise
American Patriot
Roundtrip Boston
Jun 7 - Aug 26, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,564
7 Day US & Canada Eastern
American Eagle
Amelia Island to Charleston/South Carolina
May 5, 2025 - Apr 30, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,980
7 Day US & Canada Eastern
American Independence
Roundtrip Baltimore
May 3 - 17, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,807
7 Day US & Canada Eastern
American Liberty
Charleston/South Carolina to Amelia Island
May 3, 2025 - May 16, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,465
14 Day US & Canada Eastern
American Eagle
Amelia Island to Washington, D.C.
May 19, 2025 & May 13, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,480
8 Day Alaska-Inside Passage
American Constellation
Roundtrip Juneau
May 25, 2025 - Sep 7, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,336
8 Day Alaska-Inside Passage
American Constitution
Roundtrip Juneau
Jul 7, 2025 - Aug 10, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,440
11 Day Alaska-Inside Passage
American Constitution
Roundtrip Juneau
Jun 7, 2025 - Aug 27, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,876
14 Day Alaska-N./S. Bound
American Constellation
Seattle to Juneau
May 12, 2025 & May 11, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $11,613
15 Day Alaska-N./S. Bound
American Constellation
Juneau to Seattle
Sep 15, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,514
15 Day Alaska-N./S. Bound
American Constitution
Juneau to Seattle
Sep 7, 2025 & Sep 6, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,514
15 Day Alaska-N./S. Bound
American Constellation
Fairbanks to Juneau
Jul 16 & Aug 26, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $13,959
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Melody
Saint Louis to Saint Paul
Jul 18, 2025 - Oct 10, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Serenade
Saint Louis to Saint Paul
Jul 11, 2025 - Aug 8, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
Upper Mississippi River Cruise
15 Day US & Canada River Cruises
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Saint Louis to Pittsburgh
Jun 20, 2025 - Aug 1, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,638
7 Day US & Canada Pacific
American Constitution
Roundtrip Seattle
Apr 26, 2025 - Oct 18, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,049
7 Day US & Canada Pacific
American Spirit
Roundtrip Seattle
May 10, 2025 - Sep 19, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,049
7 Day US & Canada Pacific
American Constellation
Roundtrip Seattle
Apr 28, 2025 - Oct 20, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,049

All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.

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