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American Cruise Line Cruise Deals
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
Best American Cruise Line Deals by Destination
New Orleans - New Orleans
Fr $3,265
Memphis - New Orleans
Fr $3,365
New Orleans - New Orleans
7 Day US & Canada River Cruises
Queen of the Mississippi
New Orleans to Memphis
Mar 13 - Nov 13, 2021
Queen of the Mississippi
New Orleans to Memphis
Mar 13 - Nov 13, 2021
Fr $3,760
New Orleans - New Orleans
Fr $3,760
Memphis - New Orleans
7 Day US & Canada River Cruises
American Jazz New Ship!
Memphis to New Orleans
Feb 28 - Dec 28, 2021
American Jazz New Ship!
Memphis to New Orleans
Feb 28 - Dec 28, 2021
Fr $4,065
New Orleans - Memphis
7 Day US & Canada River Cruises
American Jazz New Ship!
New Orleans to Memphis
Feb 21 - Dec 20, 2021
American Jazz New Ship!
New Orleans to Memphis
Feb 21 - Dec 20, 2021
Fr $4,065
Fall Foliage Cruise
Fr $4,095
Fall Foliage Cruise
Fr $4,490
Fall Foliage Cruise
Fr $4,490
Fall Foliage Cruise
Fr $5,135
Fall Foliage Cruise
Fr $5,315
Fall Foliage Cruise
Fr $5,315
COLUMBIA & SNAKE RIVER CRUISE
Fr $2,220
COLUMBIA RIVER CRUISE
Fr $2,280
COLUMBIA & SNAKE RIVER CRUISE
Fr $3,365
COLUMBIA & SNAKE RIVER CRUISE
Fr $3,760
COLUMBIA & SNAKE RIVER CRUISE
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
Fr $4,465
PUGET SOUND AND SAN JUAN ISLANDS CRUISE
Fr $4,780
COLUMBIA & SNAKE RIVER CRUISE
Fr $5,275
New England Cruise
Fr $4,585
New England Cruise
Fr $4,585
New England Cruise
Fr $4,745
Grand New England Cruise
Fr $1,047
Grand New England Cruise
Fr $5,655
Mid-Atlantic Inland Passage Cruise
Fr $3,290
Chesapeake Bay Cruise
Fr $3,375
Great Rivers of Florida
Fr $3,465
Historic South and Golden Isles Cruise
Fr $3,540
American Revolution Cruise
10 Day US & Canada River Cruises
American Constitution
Roundtrip Baltimore
Apr 7, 2021 - Nov 3, 2022
American Constitution
Roundtrip Baltimore
Apr 7, 2021 - Nov 3, 2022
Fr $4,770
Inside Passage Cruise
Fr $5,100
Southeast Alaska Cruise
Fr $5,595
Inside Passage Cruise
Fr $7,485
North/South Bound
Fr $8,460
North / South Bound
Fr $8,460
Mississippi River Gateway Cruise
Fr $4,035
Upper Mississippi River Cruise
Fr $4,035
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
Fr $4,875
Upper Mississippi River Cruise
10 Day US & Canada River Cruises
Queen of the Mississippi
Pittsburgh to Saint Louis
Aug 20 - Sep 29, 2021
Queen of the Mississippi
Pittsburgh to Saint Louis
Aug 20 - Sep 29, 2021
Fr $4,970
Upper Mississippi River Cruise
10 Day US & Canada River Cruises
Queen of the Mississippi
Saint Louis to Pittsburgh
Aug 10, 2021 - Aug 6, 2022
Queen of the Mississippi
Saint Louis to Pittsburgh
Aug 10, 2021 - Aug 6, 2022
Fr $5,070
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
