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American Cruise Line Cruise Deals
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
Featured American Cruise Line Deals
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Save up to $1,000: per cabin on select Cape Codder Summer Cruise sailings
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Save up to $1,000: per cabin on select Music Cities Cruise sailings
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Save up to $1,000: per cabin on select Columbia & Snake River Cruise sailings
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Save up to $600: per cabin on select Last Frontier Cruise sailings
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Included Amenities: FREE Wi-Fi & Beverages
- Complimentary Wi-Fi
- Complimentary cocktail hour held each evening
- Afternoon tea service in the Sky Lounge
- Breakfast room service
- Culinary program featuring locally sourced ingredients
Best American Cruise Line Deals by Destination
Memphis - New Orleans
7 Day US & Canada River Cruises
Queen of the Mississippi
Memphis to New Orleans
Nov 20 & Dec 4, 2021
Queen of the Mississippi
Memphis to New Orleans
Nov 20 & Dec 4, 2021
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,540
New Orleans - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
New Orleans - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Memphis - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,575
New Orleans - Memphis
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,875
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,490
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,490
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,490
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,315
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,315
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $2,220
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,585
New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,585
New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,585
Grand New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $1,047
Grand New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $6,045
Mid-Atlantic Inland Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,290
Great Rivers of Florida
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
American Revolution Cruise
10 Day US & Canada River Cruises
American Constitution
Roundtrip Baltimore
Oct 25, 2021 - Nov 3, 2022
American Constitution
Roundtrip Baltimore
Oct 25, 2021 - Nov 3, 2022
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,770
Inside Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,100
Inside Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $7,980
North / South Bound
- Included Amenities: FREE Wi-Fi & Beverages
Fr $8,460
Southeast Alaska Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $9,450
North/South Bound
- Included Amenities: FREE Wi-Fi & Beverages
Fr $9,450
Mississippi River Gateway Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,875
Upper Mississippi River Cruise
10 Day US & Canada River Cruises
Queen of the Mississippi
Pittsburgh to Saint Louis
Aug 20 - Sep 29, 2021
Queen of the Mississippi
Pittsburgh to Saint Louis
Aug 20 - Sep 29, 2021
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,970
Upper Mississippi River Cruise
10 Day US & Canada River Cruises
Queen of the Mississippi
Saint Louis to Pittsburgh
Aug 10, 2021 - Aug 6, 2022
Queen of the Mississippi
Saint Louis to Pittsburgh
Aug 10, 2021 - Aug 6, 2022
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,070
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
