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American Cruise Line Cruise Deals
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
Featured American Cruise Line Deals
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Save up to $1,000: per cabin on select Cape Codder Summer Cruise sailings
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Save up to $1,000: per cabin on select Music Cities Cruise sailings
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Save up to $1,000: per cabin on select Columbia & Snake River Cruise sailings
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Save up to $600: per cabin on select Last Frontier Cruise sailings
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Included Amenities: FREE Wi-Fi & Beverages
- Complimentary Wi-Fi
- Complimentary cocktail hour held each evening
- Afternoon tea service in the Sky Lounge
- Breakfast room service
- Culinary program featuring locally sourced ingredients
Best American Cruise Line Deals by Destination
New Orleans to Memphis
7 Day US & Canada River Cruises
Queen of the Mississippi
New Orleans to Memphis
Feb 26, 2022 - Apr 22, 2023
Queen of the Mississippi
New Orleans to Memphis
Feb 26, 2022 - Apr 22, 2023
- Included Amenities: FREE Wi-Fi & Beverages
Fr $573
New Orleans - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,265
New Orleans - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,265
New Orleans - New Orleans
7 Day US & Canada River Cruises
Queen of the Mississippi
Roundtrip New Orleans
Jul 16, 2022 - Jul 15, 2023
Queen of the Mississippi
Roundtrip New Orleans
Jul 16, 2022 - Jul 15, 2023
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
Memphis - New Orleans
7 Day US & Canada River Cruises
Queen of the Mississippi
Memphis to New Orleans
Feb 19, 2022 - May 13, 2023
Queen of the Mississippi
Memphis to New Orleans
Feb 19, 2022 - May 13, 2023
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
New Orleans - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Memphis - New Orleans
7 Day US & Canada River Cruises
Queen of the Mississippi
Memphis to New Orleans
Nov 20 & Dec 4, 2021
Queen of the Mississippi
Memphis to New Orleans
Nov 20 & Dec 4, 2021
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Memphis - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,560
Memphis - New Orleans
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,575
New Orleans - Memphis
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,875
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,490
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,490
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,315
COLUMBIA RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $2,280
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $2,355
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,465
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,585
New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,450
Grand New England Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $1,047
Mid-Atlantic Inland Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,290
Great Rivers of Florida
- Included Amenities: FREE Wi-Fi & Beverages
Fr $3,760
American Revolution Cruise
10 Day US & Canada River Cruises
American Constitution
Roundtrip Baltimore
Oct 25, 2021 - Nov 3, 2022
American Constitution
Roundtrip Baltimore
Oct 25, 2021 - Nov 3, 2022
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,770
Inside Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $5,100
Inside Passage Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $7,980
Southeast Alaska Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $8,860
North/South Bound
- Included Amenities: FREE Wi-Fi & Beverages
Fr $8,860
North / South Bound
- Included Amenities: FREE Wi-Fi & Beverages
Fr $8,955
Mississippi River Gateway Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,035
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
American Melody New Ship!
Saint Louis to Saint Paul
Jul 22 - Oct 28, 2022
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,875
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Beverages
Fr $4,690
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
