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American Cruise Line Cruise Deals
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
Featured American Cruise Line Deals
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Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
- Complimentary cocktail hour held each evening
- Afternoon tea service in the Sky Lounge
- Breakfast room service
Best American Cruise Line Deals by Destination
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,688
8 Day US & Canada River Cruises
American West
Clarkston to Portland/Oregon
Apr 26, 2024 - Jul 20, 2026
American West
Clarkston to Portland/Oregon
Apr 26, 2024 - Jul 20, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,688
8 Day US & Canada River Cruises
American Pride
Portland/Oregon to Clarkston
Apr 28, 2024 - Nov 9, 2026
American Pride
Portland/Oregon to Clarkston
Apr 28, 2024 - Nov 9, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,391
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada River Cruises
American Pride
Clarkston to Portland/Oregon
May 5, 2024 - Nov 2, 2026
American Pride
Clarkston to Portland/Oregon
May 5, 2024 - Nov 2, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,485
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,163
COLUMBIA & SNAKE RIVER CRUISE
8 Day US & Canada River Cruises
American Harmony
Clarkston to Portland/Oregon
May 2, 2024 - Dec 29, 2026
American Harmony
Clarkston to Portland/Oregon
May 2, 2024 - Dec 29, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
COLUMBIA & SNAKE RIVER CRUISE
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,123
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,579
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,703
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,911
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,574
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,163
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,163
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,203
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,391
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,391
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $2,946
Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,366
Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,594
Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
8 Day US & Canada River Cruises
American Symphony
New Orleans to Memphis
Apr 26, 2024 - Dec 24, 2026
American Symphony
New Orleans to Memphis
Apr 26, 2024 - Dec 24, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,980
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,980
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,515
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,703
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,911
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,911
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,079
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,079
Fall Foliage Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,926
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,926
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,703
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,703
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,683
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $10,564
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,381
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,683
7 Day US & Canada Eastern
American Liberty
Charleston/South Carolina to Amelia Island
Nov 23, 2024 - May 16, 2026
American Liberty
Charleston/South Carolina to Amelia Island
Nov 23, 2024 - May 16, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,465
American Revolution Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,188
14 Day US & Canada Eastern
American Independence
Baltimore to Amelia Island
Nov 6, 2024 - Nov 4, 2026
American Independence
Baltimore to Amelia Island
Nov 6, 2024 - Nov 4, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,237
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,237
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,594
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,109
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $8,079
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,688
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,688
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Serenade
Saint Louis to Saint Paul
Jul 16, 2024 - Aug 8, 2026
American Serenade
Saint Louis to Saint Paul
Jul 16, 2024 - Aug 8, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,094
Upper Mississippi River Cruise
7 Day US & Canada River Cruises
American Melody
Saint Louis to Saint Paul
Jul 26, 2024 - Oct 10, 2026
American Melody
Saint Louis to Saint Paul
Jul 26, 2024 - Oct 10, 2026
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,257
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $6,044
Upper Mississippi River Cruise
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,094
Grand Puget Sound
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,248
Puget Sound & San Juan Islands
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,347
Puget Sound & San Juan Islands
- Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,540
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
