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Mississippi River Cruises

Mississippi River Cruises

About Mississippi River Cruises

Mississippi River Map

One of the most important U.S. waterways, and one of the most colorful, is the mighty Mississippi River. On a Mississippi River cruise American history comes to life. The broad vistas take you through America's heartland, past beautifully restored antebellum plantations, and into incredible cities and towns. Explore civil war battlegrounds and the historical homes of Mark Twain and Abraham Lincoln.

Music is an integral part of the Mississippi River culture. There is no better place to experience the blues than in Memphis where you can visit the historical Graceland. Nashville brings country music alive at the Grand Ole Opry. Be surrounded by incredible Jazz surround in New Orleans. Let a Mississippi River cruise show you some of the best that America has to offer.

Best Mississippi River Cruise Deals

American Cruise Line
7 Day Mississippi River Cruise
American Heritage
Roundtrip New Orleans
Oct 28 - Nov 15, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $2,946
Viking River Cruises
7 Day Mississippi River Cruise
Viking Mississippi
Roundtrip New Orleans
Nov 23 - Dec 28, 2024
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $3,499
American Cruise Line
7 Day Mississippi River Cruises
American Symphony
Roundtrip New Orleans
Dec 13, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,451
Viking River Cruises
7 Day Mississippi River Cruises
Viking Mississippi
New Orleans to Memphis
Jul 27 & Sep 28, 2024
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $7,199
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Memphis to Nashville
Jul 2, 2024 - Oct 14, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Memphis to New Orleans
Jul 16 - Nov 19, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Heritage
Memphis to New Orleans
Sep 23 - Oct 21, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,787
American Cruise Line
8 Day Mississippi River Cruise
American Melody
Memphis to Nashville
Sep 20, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Serenade
Memphis to New Orleans
Nov 12, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Melody
Memphis to New Orleans
Aug 23 - Nov 29, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
Memphis to New Orleans
Aug 23 - Dec 29, 2024
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
Viking River Cruises
11 Day Mississippi River Cruise
Viking Mississippi
Memphis to New Orleans
Nov 14, 2024
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Call
Viking River Cruises
14 Day Mississippi River Cruise
Viking Mississippi
Memphis to Saint Paul
Jun 29 - Oct 5, 2024
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $9,299
American Cruise Line
7 Day Mississippi River Cruise
American Heritage
Roundtrip New Orleans
Mar 29 - Nov 15, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,441
Viking River Cruises
7 Day Mississippi River Cruise
Viking Mississippi
Roundtrip New Orleans
Jan 4 - Dec 27, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $3,999
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Memphis to New Orleans
Mar 4 - Nov 11, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Memphis to Nashville
Jun 10 - Oct 14, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Nashville to Memphis
Jun 17 - Oct 21, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
New Orleans to Memphis
Feb 25 - Nov 4, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day US & Canada River Cruises
American Symphony
Nashville to Chattanooga
Apr 29 - Oct 14, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,792
American Cruise Line
8 Day Mississippi River Cruise
American Serenade
New Orleans to Memphis
Feb 21 - Oct 16, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Melody
New Orleans to Memphis
Mar 28 - Nov 15, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
New Orleans to Memphis
Mar 4 - Dec 24, 2025
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
Viking River Cruises
11 Day Mississippi River Cruise
Viking Mississippi
Memphis to New Orleans
Jan 16 - Dec 11, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Call
Viking River Cruises
11 Day Mississippi River Cruise
Viking Mississippi
New Orleans to Memphis
Jan 9 - Dec 4, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Call
Viking River Cruises
11 Day Mississippi River Cruise
Viking Mississippi
Saint Louis to Minneapolis
Jun 26 - Oct 2, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Call
Viking River Cruises
14 Day Mississippi River Cruise
Viking Mississippi
Saint Paul to New Orleans
Jul 5 - Oct 11, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $12,499
Viking River Cruises
21 Day Mississippi River Cruise
Viking Mississippi
New Orleans to Saint Paul
Jun 14 - Sep 20, 2025
  • All Inclusive Cruising: FREE Wi-Fi, Shore Excursions & Beverages
Fr $14,699
American Cruise Line
7 Day Mississippi River Cruise
American Heritage
Roundtrip New Orleans
Mar 29 - Nov 15, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $3,441
American Cruise Line
7 Day Mississippi River Cruise
American Melody
Saint Louis to Saint Paul
Jul 18 - Oct 10, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,490
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Memphis to Nashville
Jun 10 - Oct 14, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Splendor
Nashville to Memphis
Jun 17 - Oct 21, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,084
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
Nashville to Chattanooga
Apr 29 - Oct 14, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,792
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
Chattanooga to Nashville
May 6 - Oct 21, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,792
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
Memphis to Nashville
Apr 22 - Sep 9, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $4,792
American Cruise Line
8 Day Mississippi River Cruise
American Symphony
New Orleans to Memphis
Feb 18 - Dec 24, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
8 Day Mississippi River Cruise
American Serenade
New Orleans to Memphis
Feb 21 - Oct 16, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $5,139
American Cruise Line
15 Day Mississippi River Cruise
American Heritage
Saint Louis to Pittsburgh
Jul 11 & Aug 8, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,470
American Cruise Line
15 Day Mississippi River Cruise
American Heritage
Pittsburgh to Saint Louis
Jul 25 & Aug 22, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $7,470
American Cruise Line
15 Day Mississippi River Cruise
American Melody
Pittsburgh to Saint Louis
Jul 4 & Aug 15, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,005
American Cruise Line
15 Day Mississippi River Cruise
American Melody
Saint Louis to Pittsburgh
Jun 20 & Aug 1, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $9,663
American Cruise Line
22 Day Mississippi River Cruise
American Melody
New Orleans to Saint Paul
May 23, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $16,474
American Cruise Line
22 Day Mississippi River Cruise
American Serenade
New Orleans to Saint Paul
Jun 13, 2026
  • Included Amenities: FREE Wi-Fi & Complimentary cocktail hour each evening and Much More!
Fr $16,474

All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.

Due to the small ship size river cruises book up early and quickly. It is highly recommended to book your river cruise well in advance. All prices and availability are subject to change at any time. Please call to verify the availability and rates.

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